Indian Journal of Pathology and Microbiology
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Year : 1995  |  Volume : 38  |  Issue : 1  |  Page : 55-62

Wilms' tumour : a clinicopathologic study with special reference to its morphologic variants.


Department of Pathology and Surgery, King George's Medical College, Lucknow, India

Correspondence Address:
S Sharma
Department of Pathology and Surgery, King George's Medical College, Lucknow, India

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Source of Support: None, Conflict of Interest: None


PMID: 8919470

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Twenty five cases of Wilms' tumour were studied with special reference to their morphological variations. Wilms' tumour constituted 7.6% of all the malignant tumours of childhood and 50% of renal malignancies. Male/female ratio was 4:1; the mean age being 3.5 years. Left side was commonly involved (60.9%) center dot bilateral involvement in one case (4.3%). Morphologic study revealed triphasic pattern in 60% cases, biphasic (epithelial + stromal) in 12% and monophasic pattern in 28%. Other features observed were myxomatous degeneration, rhabdomyoblasts, calcification and squamous epithelial pearls seen in 20%, 12%, 8% and 4% respectively.


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