Indian Journal of Pathology and Microbiology
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Year : 1995  |  Volume : 38  |  Issue : 2  |  Page : 199-201

Immunohistochemical localisation of carcinoembryonic antigen (CEA) in malignant epithelial ovarian tumours using monoclonal antibodies.


Department of Pathology, B.J. Medical College, Pune

Correspondence Address:
N Gogate
Department of Pathology, B.J. Medical College, Pune

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Source of Support: None, Conflict of Interest: None


PMID: 8919110

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The localization of carcinoembryonic antigen (CEA) in malignant epithelial ovarian tumours was studied using immunohistochemistry. The tissue included in the study consisted of 38 ovarian cancers : 14 mucinous adenocarcinomas, 23 serous adenocarcinomas and 1 endometroid carcinoma. Peroxidase-antiperoxidase staining technique using monoclonal antibodies to CEA was used on routinely fixed paraffin embedded tissues. CEA positivity was observed in all (100%) mucinous adenocarcinomas whereas only one case of serous cyst a denocarcinoma (4.3%) was weakly positive. The only case endometroid carcinoma encountered showed patchy CEA positivity.


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