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Indian Journal of Pathology and Microbiology
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Year : 1995  |  Volume : 38  |  Issue : 3  |  Page : 239-43

Paraproteins and plasma cell dyscrasias.


Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh

Correspondence Address:
T Karmakar
Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh

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Source of Support: None, Conflict of Interest: None


PMID: 8819653

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Serum protein electrophoresis done on 1100 patients with various diseases in one year demonstrated M-band in 31 patients. Most (87%) had the classical features of plasma cell dyscrasia (PCD), however a few had unusual presentations which are highlighted. A 22-year-old male operated for a massive tumour of the scapula clinically diagnosed as chondrosarcoma revealed plasmacytoma with amyloid on histology. Another case of kala-azar presented with features akin to that of PCD and one case had dual malignancies. Such a high incidence of PCDs with varied picture in a short time is not usually seen in other parts of this country; a fact which may be due to lack of awareness.


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