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Year : 1997  |  Volume : 40  |  Issue : 1  |  Page : 21-5

Role of redchilli (Capsaicin) in the formation of colonic carcinoma.


Department of Biochemistry, Faculty of Medicine, Annamalai University, Tamil Nadu, India

Correspondence Address:
S Chitra
Department of Biochemistry, Faculty of Medicine, Annamalai University, Tamil Nadu, India

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Source of Support: None, Conflict of Interest: None


PMID: 9145607

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The effect of feeding redchilli (Capsaicin) powder on the histopathological changes occurring in the colonic mucosa was studied in rats. These animals were compared with those treated with a colonic carcinogen 1,2-dimethylhydrazine (DMH). Animals fed with redchilli, dimethylhydrazine, dimethylhydrazine plus redchilli powder showed polyp and dysplasia, malignant tumour and malignant tumour with transitional area of dysplasia.


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