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Year : 1997  |  Volume : 40  |  Issue : 2  |  Page : 129-31

Serological evidence for active Epstein-Barr virus infection in multifocal choroiditis.


Vision Research Foundation, Medical Research Foundation Sankara Nethralaya, Madras

Correspondence Address:
P S Bhende
Vision Research Foundation, Medical Research Foundation Sankara Nethralaya, Madras

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Source of Support: None, Conflict of Interest: None


PMID: 9257497

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Six patients, consisting of 4 males and 2 females with mean average age fo 29.20 years, with variable picture of multifocal choroiditis were serologically investigated for their association with Epstein-Barr Virus (EBV) infection. IgG and IgM antibodies to EBV-Virus Capsid Antigen (VCA) were assayed by immunoperoxidase method on EBV infected lymphoblast cells (P3HR-1 Burkitt's lymphoma cell line). In these patients definite serological evidence of EBV infection with high titres of IgG and IgM antibodies to EBV-VCA was demonstrated suggestive of active continuing or persisting EBV infection.


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