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Year : 2006  |  Volume : 49  |  Issue : 2  |  Page : 269-70

Hemolytic anaemia due to unstable hemoglobin arising from spontaneous mutation--a case report.


Department of Haematology, Postgraduate Institute of Medical Education and Research, Chandigarh

Correspondence Address:
S Dash
Department of Haematology, Postgraduate Institute of Medical Education and Research, Chandigarh

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Source of Support: None, Conflict of Interest: None


PMID: 16933736

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9 years old male child presented clinically with thalassaemia intermedia phenotype. Investigations revealed hemolytic anaemia due to an unstable hemoglobin. Parents were found negative for the abnormal hemoglobin, suggesting a spontaneous mutation in the child. This is the third case of unstable hemoglobin to be reported from India. Clinically it is important that unstable hemoglobin should be suspected in a patient with thalassaemia intermedia phenotype even if both parents are haematologically normal.


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