LGCmain
Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Ahead Of Print Login 
Users Online: 5251
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size
IJPM is coming out with a Special issue on "Genitourinary & Gynecological pathology including Breast". Please submit your articles for these issues
Year : 2006  |  Volume : 49  |  Issue : 3  |  Page : 345-7

Detection of HPV16 and 18 by in situ hybridization in precancerous and cancerous lesions of cervix.


Department of Pathology, Lady Hardinge Medical College & Associated Hospitals, New Delhi

Correspondence Address:
M Choudhury
Department of Pathology, Lady Hardinge Medical College & Associated Hospitals, New Delhi

Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 17001881

Rights and PermissionsRights and Permissions

Fifty cervical biopsies from women with preinvasive and invasive malignancies of uterine cervix and ten normal cervical biopsies were examined for the presence of human papilloma virus (HPV) 16 and 18 DNA sequences by in situ hybridization (ISH) method with biotinylated DNA probes. The overall positivity of HPV DNA was 48% (24/50). The positivity of HPV 16 DNA for low grade squamous intraepithelial lesion (LSIL), high grade squamous intraepithelial lesions (HSIL) and squamous cell carcinoma (SCC) were 33.33%, 45.45%, 42.30% respectively. The positivity for HPV 18 DNA for LSIL, HSIL and SCC were 0%, 18.18%, 30.76% respectively. Two cases of cervical adenocarcinomas showed positivity for HPV 18 DNA only.


[PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed536    
    Printed38    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 4    

Recommend this journal