LGCmain
Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Ahead Of Print Login 
Users Online: 2235
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size
IJPM is coming out with a Special issue on "Genitourinary & Gynecological pathology including Breast". Please submit your articles for these issues
Year : 2007  |  Volume : 50  |  Issue : 1  |  Page : 94-6

Induction of resistance to fluoroquinolones in clinical and environmental isolates of Pseudomonas aeruginosa.


Department of Microbiology, Kasturba Medical College, Manipal and Sikkim Institute of Medical Sciences, Gangtok, Sikkim

Correspondence Address:
S Vishnu Prasad
Department of Microbiology, Kasturba Medical College, Manipal and Sikkim Institute of Medical Sciences, Gangtok, Sikkim

Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 17474274

Rights and PermissionsRights and Permissions

An attempt to induce resistance to ciprofloxacin in vitro was made against clinical and environmental isolates of Pseudomonas aeruginosa. This in vitro manipulation of strains resulted in the increase of minimum inhibitory concentration from 0.4 microg/ml to 1 microg/ml of the original strains to 9.0 to 12.5 microg/ml indicating development of resistance to ciprofloxacin and a major decrease in the size of zone diameters of norfloxacin and ofloxacin indicating cross resistance to these agents. Results indicate the induced resistance to ciprofloxacin can promote development of cross resistance to other fluoroquinolones. This suggests that caution should be taken while using fluoroquinolones for the treatment of Pseudomonas aeruginosa infections.


[PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed574    
    Printed46    
    Emailed1    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal