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Indian Journal of Pathology and Microbiology
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Year : 2007  |  Volume : 50  |  Issue : 2  |  Page : 270-3

Clear cell sarcoma of the kidney--a study of seven cases over a period of three years.


Department of Pathology, Tata Memorial Hospital, Mumbai

Correspondence Address:
S Viswanathan
Department of Pathology, Tata Memorial Hospital, Mumbai

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Source of Support: None, Conflict of Interest: None


PMID: 17883043

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Clear cell sarcoma of the kidney (CCSK) can display diverse morphological patterns and mimic various other pediatric renal tumors. An accurate diagnosis of this tumour is important considering the therapeutic and prognostic implications. AIM: The present study was undertaken to describe the various histological patterns of CCSK. The histology of 7 cases and the available case files of CCSK accrued over a period of3 years were reviewed. Immunohistochemical (IHC) stains were performed in 3 cases. The histological patterns observed in this study were classical (observed in 4 cases), epithelioid trabecular, myxoid, palisading and hyaline sclerosis types. IHC revealed reactivity to vimentin and non-reactivity to cytokeratin, desmin, smooth muscle actin, neuron specific enolase (NSE) and S-100 protein. Since CCSK is essentially a histological diagnosis, the importance of an accurate diagnosis of CCSK by a pathologist cannot be overemphasized. This study describes the various histological patterns that can be observed in CCSK.


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