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Indian Journal of Pathology and Microbiology
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Year : 2007  |  Volume : 50  |  Issue : 4  |  Page : 819-21

Villoglandular papillary adenocarcinoma of cervix associated with cervical intraepithelial neoplasia : a case report and review of literature.


Department of Pathology, Melaka Manipal Medical College Manipal, Karnataka

Correspondence Address:
P S Srilatha
Department of Pathology, Melaka Manipal Medical College Manipal, Karnataka

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Source of Support: None, Conflict of Interest: None


PMID: 18306568

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Well differentiated villoglandular adenocarcinoma of uterine cervix is a rare tumour which usually occurs in young women. It is considered to be an indolent tumour with favorable prognosis and most of them were treated by conservative procedures. We report a 35 year old lady who came with complaints of 3 months amenorrhoea and an episode of spontaneous bleeding. Urine pregnancy test was negative. Physical examination revealed a cervical polyp. Histopathological findings were consistent with villoglandular papillary adenocarcinoma associated with high grade cervical intraepithelial neoplasia (CIN-3). Left parametrial and left ureteral involvement, proved by biopsy, causing left hydroureteronephrosis was detected. The patient was thus found to be in an advanced stage, stage- III b (FIGO). The patient is currently undergoing radiotherapy. A review of literature showed that only occasional cases showing disease spread have been reported, suggesting caution in the management and regular follow up of the patient.


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