LGCmain
Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Ahead Of Print Login 
Users Online: 3474
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size
BRIEF COMMUNICATION
Year : 2009  |  Volume : 52  |  Issue : 2  |  Page : 206-209

An analysis of 30 cases of myelodysplastic syndrome


1 Saumrut Laboratory, 402, Narayan complex, Near Navrangpura Bus Stand, Ahmedabad - 380 009, India
2 Conemaugh Memorial Medical center, 1086 Franklin street, johnstown PA 15905

Correspondence Address:
Ashwin P Patel
402, Narayan Complex, Near Navrangpura Bus Stand, Ahmedabad - 380 009
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.48919

Rights and Permissions

Myelodysplastic syndrome (MDS) is a clonal disorder of pluripotential stem cells of the bone marrow. The purpose of the study was to obtain epidemiological data of MDS. Thirty cases of MDS presented from April 1998 to May 2006 are included in this study. Complete blood counts were performed in an automated cell counter. Bone marrow aspiration, trephine biopsy and chromosomal study were carried out. The dry film was stained using a Romanwasky stain and Perl's stain. Fifteen cases were male and 15 cases were female. The mean age at presentation was 55 years (range 8-73 years). A majority of the patients presented with weakness (63.33%). Autoimmune manifestations in the form of joint pain were present in 13.33%. Patients were symptomatic for a prolonged period before diagnosis could be reached (average 358.8 days). A majority of the patients had MDS-refractory anemia (MDS-RA) or MDS-RA with excess blasts( MDS-RAEB-2) at presentation. Three patients had chromosomal abnormalities (27.27%). Eight patients (26.7%) were relatively young at presentation, less than 50 years of age. Three (10%) were children. A majority of the patients opted for symptomatic treatment only.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed6203    
    Printed104    
    Emailed3    
    PDF Downloaded494    
    Comments [Add]    
    Cited by others 3    

Recommend this journal