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CASE REPORT
Year : 2009  |  Volume : 52  |  Issue : 3  |  Page : 379-382

Oncocytic sialolipoma of the submandibular gland with sebaceous differentiation: A new pathological entity


1 Institute of Anatomic Pathology, S. Maria del Carmine Hospital, Piazzale S. Maria 6, 38068 Rovereto (TN), Italy
2 Department of Diagnostic and Interventional Radiology, University of Perugia, Via Brunamonti 51, 06100, Perugia, Italy
3 Department of Radiology, Budrio Hospital, Budrio (BO), Italy

Correspondence Address:
Ilaria Franceschetti
Institute of Anatomic Pathology, S. Maria del Carmine Hospital, Piazzale S. Maria 6, 38068 Rovereto (TN)
Italy
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.55000

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Case Report: We report the case of an oncocytic sialolipoma of the submandibular gland with sebaceous differentiation in a 73-year-old man. The initial symptom was a right submandibular painless mass. Ultrasonography showed a hypoechoic oval mass posterior to the submandibular gland. The tumorectomy was performed with preservation of the salivary gland. The tumor was composed of mature adipose tissue surrounded by a thin fibrous capsule, multiple nodules of oncocytes, normal ductal-acinar units with focal ductal sebaceous differentiation. Discussion: We reviewed literature of the reported cases of mixed tumors of the salivary glands composed of mature adipose tissue with oncocytosis, salivary ducts, and acini with sebaceous differentiation. Conclusions: Sialolipoma and lipoadenoma with or without oncocytosis and/or sebaceous differentiation should be considered organ-specific tumors with a distinct histological appearance and specific terminology.


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