Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Login 
Users Online: 29
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size


 
IMAGES Table of Contents   
Year : 2009  |  Volume : 52  |  Issue : 3  |  Page : 434-435
Salpingitis isthmica nodosa


Department of Pathology, SGRR Institute of Medical & Health Sciences, Dehradun, Uttaranchal, India

Click here for correspondence address and email

Date of Web Publication12-Aug-2009
 

How to cite this article:
Chawla N, Kudesia S, Azad S, Singhal M, Rai S. Salpingitis isthmica nodosa. Indian J Pathol Microbiol 2009;52:434-5

How to cite this URL:
Chawla N, Kudesia S, Azad S, Singhal M, Rai S. Salpingitis isthmica nodosa. Indian J Pathol Microbiol [serial online] 2009 [cited 2014 Oct 25];52:434-5. Available from: http://www.ijpmonline.org/text.asp?2009/52/3/434/55019


Salpingitis isthmica nodosa is a condition of the  Fallopian tube More Details characterized by nodular thickening of the tunica muscularis of the isthmic portion of the tube enclosing cystically dilated glands leading to complete obliteration of tubal lumen. [1] It is usually bilateral and the patient presents with primary infertility or recurrent ectopic pregnancies. [2] Hysterosalpingography is diagnostic of this condition.

In the present study, a 45-year-old patient presented to the gynecology department with primary infertility and dysfunctional uterine bleeding. She had taken hormonal treatment for infertility earlier and was admitted to the hospital with complaints of menorrhagia. Total abdominal hysterectomy with bilateral salpingoophrectomy was carried out. Gross examination of the uterus revealed hyperplastic endometrium along with a small intramural leiomyoma. The isthmic end of both fallopian tubes showed a grey-white nodules measuring 1.5cm in diameter [Figure 1] and the lumen was occluded with the distal portion of tubes appearing normal. Both the ovaries showed no significant pathology. Microscopic examination of bilateral nodules at the isthmus of fallopian tubes revealed cystically dilated glands surrounded by hypertrophic muscular layer with complete obliteration of tubal lumen [Figure 2].The glands were lined by ciliated columnar epithelium [Figure 3]. Few of the glands were seen infiltrating the muscular layer. Microscopic examination of uterine corpus showed endometrium displaying features of complex hyperplasia without atypia. Salpingitis isthmica nodosa involves women in the age group of 25-60 years with average age at diagnosis being 30 years. The etiology of this condition is unknown, possible causes are post-inflammatory distortion and adenomyosis-like process. [3] Microscopic examination of the nodule shows dispersed glands of tubal epithelium surrounded by broad bands of muscularis. [4] On hysterosalpingography, diagnosis may be confused with tubal endometriosis, however, presence of tubal epithelium lining the glands on histopathological examination rules out endometriosis. [5] Complex endometrial hyperplasia seen in our case could be attributed to hormonal treatment taken for infertility. The complications of salpingitis isthmica nodosa are infertility and recurrent ectopic pregnancies and hence, salpingitis isthmica nodosa is an important cause to be ruled out in such cases. [2]

 
   References Top

1.Jenkins CS,Williams SR,Schmidt GE.Salpingitis isthmica nodosa: A review of literature, discussion of clinical significance and consideration of patient management. Fertil Steril 1993;60:599-607.  Back to cited text no. 1  [PUBMED]  
2.Majumdar B,Henderson PH, Semple E. Salpingitis isthmica nodosa: A high risk for tubal pregnancy. Obstet Gynecol Surv 1983;62:73-8.  Back to cited text no. 2    
3.Green LK, Kott ML. Histopathologic findings in ectopic tubal pregnancy. Int J Gynecol Pathol 1989;8:255-62.  Back to cited text no. 3  [PUBMED]  
4.Benjamin CL, Beaver DC. Pathogenesis of salpingitis isthmica nodosa. Am J Clin Pathol 1951;21:212- 22.  Back to cited text no. 4  [PUBMED]  
5.McComb PF, Rowe TC. Salpingitis isthmica nodosa: Evidence it is a progressive disease. Fertil Steril 1989;51:542-5.  Back to cited text no. 5  [PUBMED]  

Top
Correspondence Address:
Nitin Chawla
124/7, Rajender Nagar, Street-4, Lane-8, Dehradun, Uttarakhand - 248 001
India
Login to access the Email id


DOI: 10.4103/0377-4929.55019

PMID: 19679986

Get Permissions



    Figures

  [Figure 1], [Figure 2], [Figure 3]

This article has been cited by
1 Imaging of Female Infertility
Katherine Kaproth-Joslin,Vikram Dogra
Radiologic Clinics of North America. 2013; 51(6): 967
[Pubmed]
2 Lipomesosalpinx: a rare possible missed tubal factor of infertility
Atef Darwish
Gynecological Surgery. 2013;
[Pubmed]
3 Xanthogranulomatous salpingitis as a rare pathologic aspect of chronic active pelvic inflammatory disease
Yener, N., Ilter, E., Midi, A.
Indian Journal of Pathology and Microbiology. 2011; 54(1): 141-143
[Pubmed]



 

Top
 
  Search
 
  
  
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Email Alert *
    Add to My List *
* Registration required (free)  


    References
    Article Figures

 Article Access Statistics
    Viewed3996    
    Printed73    
    Emailed5    
    PDF Downloaded256    
    Comments [Add]    
    Cited by others 3    

Recommend this journal