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LETTER TO EDITOR Table of Contents   
Year : 2010  |  Volume : 53  |  Issue : 2  |  Page : 372
Fine needle aspiration cytology findings in human immunodeficiency virus lymphadenopathy


1 Medical officer, Washford Road, Hilton, Derbyshire, DE 65 5 HN, United Kingdom
2 Department of Surgery, Derby General Hospital, Derby, United Kingdom

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Date of Web Publication12-Jun-2010
 

How to cite this article:
Jahnavi S, Nyasavajjala S M. Fine needle aspiration cytology findings in human immunodeficiency virus lymphadenopathy. Indian J Pathol Microbiol 2010;53:372

How to cite this URL:
Jahnavi S, Nyasavajjala S M. Fine needle aspiration cytology findings in human immunodeficiency virus lymphadenopathy. Indian J Pathol Microbiol [serial online] 2010 [cited 2019 Nov 23];53:372. Available from: http://www.ijpmonline.org/text.asp?2010/53/2/372/64284


Sir,

While we were searching the internet for articles on fine needle aspiration cytology (FNAC) of lymphadenopathy in acquired immune deficiency syndrome (AIDS), we came across the article by Vanisri et al.[1] published in your journal in 2008. While viewing the images, the [Figure 5] described by the authors as acute suppurative lymphadenitis, in fact shows 'negative images' of acid fast bacilli described in the literature. Either the authors have not noticed it or not aware of the finding or have not highlighted the same in the text.

Negative images, is the finding described in the foam cells of lepromatous or histoid leprosy, where one finds the unstained lepra bacilli as negatively stained inclusions in the cells, and they become obvious when stained with Fite-Faraco stain. [2] Similar observation has been made in the lymph node aspirates in HIV and AIDS. Wannakrairot et al.[3] have observed pseudo-Gaucher cell response seen in HIV lymphadenopathy. Dunn et al.[4] report needle like inclusions, which are actually acid fast bacilli within the so-called pseudo-Gaucher cells.

This letter is to sensitize the readers to examine the smears stained with conventional stains only, for these 'negative images' of acid fast bacilli and do special stains when suppurative morphology is seen in the needle aspirates.

 
   References Top

1.Vanisri HR, Nandini NM, Sunila R. Fine-needle aspiration cytology findings in human immunodeficiency virus lymphadenopathy. Indian J Pathol Microbiol 2008;51:481-4.  Back to cited text no. 1  [PUBMED]  Medknow Journal  
2.Triscott JA, Nappi O, Ferrara G, Wick MR. "Pseudoneoplastic" leprosy. Leprosy revisited. Am J Dermatopathol 1995;17:297-302.  Back to cited text no. 2  [PUBMED]    
3.Wannakrairot P, Leong TY, Leong AS. The morphological spectrum of lymphadenopathy in HIV infected patients. Pathology 2007;39:223-7.  Back to cited text no. 3  [PUBMED]  [FULLTEXT]  
4.Dunn P, Kuo MC, Sun CF. Pseudo-Gaucher cells in mycobacterial infection: A report of 2 cases. J Clin Pathol 2005;58:1113-4.  Back to cited text no. 4  [PUBMED]  [FULLTEXT]  

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Correspondence Address:
S Jahnavi
1, Washford Road, Hilton, Derbyshire, DE 65 5 HN
United Kingdom
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.64284

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