Indian Journal of Pathology and Microbiology
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Year : 2012  |  Volume : 55  |  Issue : 4  |  Page : 563-565

Follicular hybrid cyst on the cheek: A combination of infundibular, isthmic, and pilomatrical differentiation

Department of Plastic and Reconstructive Surgery, St. Vincent's hospital, College of Medicine, The Catholic University of Korea, Korea

Correspondence Address:
Min-Cheol Kim
Department of Plastic Surgery, St. Vincent Hospital, 93-6, Ji Dong, Paldal-gu, Suwon, Gyeonggi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.107823

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A hybrid cyst is a rare condition which includes any type of cyst arising from the various parts of the pilosebaceous unit. We report a case of hybrid cyst with infundibular, isthmic, and pilomatrical differentiation. A 12-year-old boy presented with a mass on the right cheek. The physical examination revealed an oval-shaped, dark-gray protruding mass with dimensions of 0.9 cm × 0.6 cm that was non-tender to palpation. The mass was totally excised. The diagnosis of a hybrid cyst was confirmed by histological evaluation. It was a well-encapsulated mass and showed combined histologic features of infundibular, isthmus, and pilomatrical differentiation. The hybrid cyst is a follicular cyst that includes two or more components of a cystic lesion arising from the pilosebaceous unit. Occasionally, there have been reports of hybrid cysts consisting of two components in differentiation, but those showing more than two components of differentiation have been extremely rare. The pathogenesis of this unusual disease is not yet known.

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