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Indian Journal of Pathology and Microbiology
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CASE REPORT
Year : 2013  |  Volume : 56  |  Issue : 3  |  Page : 303-305

Chronic lymphocytic leukemia developing in a case of chronic myelogenous leukemia - accelerated phase: A rare case with review of the literature


1 Department of Hematology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh, India
2 Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh, India

Correspondence Address:
Narender Kumar
Department of Hematology, Level 5, Research Block A, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.120406

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Chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL) are two different and common hematological neoplasms. Their coexistence is rare, especially CLL developing in a patient of CML. Till date, only a few cases are reported and all had chronic myeloid leukemia - chronic phase earlier. We report the first case of CLL developing in a patient initially diagnosed in an accelerated phase of chronic myeloid leukemia. The clonality of both CML and CLL was proven by cytogenetic, molecular and flow cytometric studies.


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