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CASE REPORT
Year : 2014  |  Volume : 57  |  Issue : 1  |  Page : 98-100

Triple composite tumor of stomach: A rare combination of alpha fetoprotein positive hepatoid adenocarcinoma, tubular adenocarcinoma and large cell neuroendocrine carcinoma


Department of Pathology & Lab Medicine, Medanta-The Medicity Hospital, Gurgaon, Haryana, India

Correspondence Address:
Ritesh Sachdev
A 803, Plot No 7 A. Navrattan Apartments, Sector 23, Dwarka, New Delhi - 110 077
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.130912

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A 50-year-old male patient presented with pain abdomen of 6 months duration. Computed tomography scan revealed a large mass in the stomach occluding the lumen. Histopathology revealed a triple composite tumor comprising of tubular adenocarcinoma arising on a background of high-grade dysplasia, hepatoid adenocarcinoma (positive for Hep Par-1 and alpha fetoprotein) and large cell neuroendocrine carcinoma (positive for synaptophysin and chromogranin) with nodal metastasis.Triple composite tumors are distinctly rare with few reports in literature.


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