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CASE REPORT
Year : 2016  |  Volume : 59  |  Issue : 2  |  Page : 212-215

Persistent Müllerian duct syndrome of mixed anatomical variant (combined male and female type) with mixed germ cell tumor of left intra-abdominal testis


1 Department of Pathology, GSL Medical College and General Hospital, Rajahmundry, Andhra Pradesh, India
2 Department of Medical Oncology, GSL Medical College and General Hospital, Rajahmundry, Andhra Pradesh, India

Correspondence Address:
Manisha Mohapatra
Department of Pathology, GSL Medical College and General Hospital, NH - 16, Lakshmipuram, Rajahmundry - 533 296, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.182036

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Persistent Müllerian duct syndrome (PMDS) is a rare form of internal male pseudohermaphroditism characterized by retention of Müllerian duct derivatives in a phenotypically and karyotypically male patient. Deficiency of anti-Müllerian hormone (AMH) secretion or resistance to AMH action due to defective AMH-II receptor is presumed to cause such syndrome in the majority of cases. About 158 PMDS cases have been reported so far, out of which 31 cases are associated with testicular neoplasms. Herein, we describe an interesting case of young male initially diagnosed and treated for inguinal hernia, but finally diagnosed as “PMDS of mixed anatomical variant (combined male and female type) with mixed germ cell tumor of left intra-abdominal testis” comprising components of seminoma and yolk sac tumor and treated successfully.


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