Indian Journal of Pathology and Microbiology
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Year : 2016  |  Volume : 59  |  Issue : 3  |  Page : 410-412

Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma

1 Department of Pathology, Hematopathology Laboratory, Tata Memorial Hospital, Mumbai, Maharashtra, India
2 Department of Cancer Cytogenetics, Tata Memorial Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Sumeet Gujral
Department of Pathology, Hematopathology Laboratory, No 727, Annexe Building, Tata Memorial Hospital, Dr. E Borges Road, Parel (East), Mumbai - 400 012, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.188129

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Surface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precursor and mature B-cell neoplasm.

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