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CASE REPORT
Year : 2016  |  Volume : 59  |  Issue : 4  |  Page : 521-523

An atypical nonsebaceous lymphadenoma with diffuse lymphoepithelial differentiation


1 Department of Pathology, School of Medicine, Chungnam National University, Daejeon, Republic of Korea
2 Department of Radiology, School of Medicine, Chungnam National University, Daejeon, Republic of Korea

Correspondence Address:
Jin Man Kim
Department of Pathology, School of Medicine, Chungnam National University, Munwha-Dong, Jung-Gu, Daejeon 301-131
Republic of Korea
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.191810

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Nonsebaceous lymphadenoma is an uncommon salivary gland tumor. It consists of lymphoid and epithelial components that lack sebaceous differentiation. Herein, we present a 44-year-old woman with left a submandibular gland tumor. The tumor is well-circumscribed and solid without ductal or cystic formation. The epithelial cells intermingle with lymphoplasma cells. The epithelial cells show moderate cytologic atypia and a few mitoses with no viral infection. Histologically, the tumor had features of nonsebaceous lymphadenoma with unusual findings of nuclear atypia and marked lymphoepithelial differentiation. Atypical nonsebaceous lymphadenoma with diffuse lymphoepithelial differentiation is rare and important to recognize to avoid misdiagnosis.


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