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CLINICOPATHOLOGIC CONFERENCE
Year : 2017  |  Volume : 60  |  Issue : 1  |  Page : 92-96

A 54-year-old male with rapidly progressive neurologic syndrome: Clinicopathologic correlation of a rare diagnosis


1 Department of Pathology, Command Hospital Air Force, Bengaluru, Karnataka, India
2 Department of Medicine, Command Hospital Air Force, Bengaluru, Karnataka, India

Correspondence Address:
Deepti Mutreja
Department of Pathology, Command Hospital Air Force, Bengaluru - 560 007, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.200026

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Diagnosis of systemic lupus erythematosus (SLE) as primary presentation with central nervous system involvement as a rapidly progressive neurologic syndrome is extremely rare. We present a rare case of a 54-year-old hypertensive male patient, who presented with a fulminant neurologic syndrome. He presented with cerebellar and meningeal signs, aseptic meningitis and had a rapid downhill course following admission. A postmortem revealed feature of systemic connective tissue fulfilling diagnostic criteria of SLE with lupus cerebritis.


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