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CASE REPORT
Year : 2017  |  Volume : 60  |  Issue : 3  |  Page : 421-423

Undiagnosed senile systemic amyloidosis with mesenteric angiopathy leading to fatal outcomes: Two case series with a review of literature


1 Department of Pathology, University of Michigan, Ann Arbor, MI, USA
2 Department of Pathology, University of Florida, College of Medicine, Jacksonville, FL, USA
3 Department of Forensic Medicine, Maulana Azad Medical College, New Delhi, India

Correspondence Address:
Avneesh Gupta
Department of Pathology, Division of Neuropathology, 1301 Catherine Street, Room 5226 Med SCI I, Ann Arbor, MI 48109
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/IJPM.IJPM_278_16

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Amyloid mesenteric angiopathy is difficult to diagnose as gastrointestinal (GI) signs are nonspecific and radiological studies rarely identify amyloid deposits with certainty. The objective of this study was to highlight the pathological findings of amyloid mesenteric angiopathy in cases of senile systemic amyloidosis. Literature review, author's research data, and practice experience were used. Systemic amyloidosis should be considered in the differential diagnoses when evaluating nonspecific and unexplained GI in patient population aged >55 years to decrease the morbidity and fatal outcomes.


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