Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Ahead Of Print Login 
Users Online: 367
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size


 
  Table of Contents    
EDITORIAL  
Year : 2018  |  Volume : 61  |  Issue : 2  |  Page : 169
From the Editor's Desk


MD; FICPath; MIAC, DHA Professor, Department of Pathology, Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh, India

Click here for correspondence address and email

Date of Web Publication20-Apr-2018
 

How to cite this article:
Agrawal R. From the Editor's Desk. Indian J Pathol Microbiol 2018;61:169

How to cite this URL:
Agrawal R. From the Editor's Desk. Indian J Pathol Microbiol [serial online] 2018 [cited 2018 Nov 17];61:169. Available from: http://www.ijpmonline.org/text.asp?2018/61/2/169/230586




After an initial delay of the January issue, we are back into the flow with the April issue. It has been six decades since the start of Indian Journal of Pathology and Microbiology (IJPM). I would like to reinstate that the high scientific standards of the articles would be maintained.

The technical simplicity, easy availability, and comparatively lower cost enhance the role of p53 as a biomarker in risk stratification for patients with Barrett's esophagus. This has very well been mentioned by Krothapalli et al. in their article published in this issue.[1]

Lymphangiogenesis correlates with a poor prognosis in invasive ductal carcinoma (IDC) breast. D240 antibody, a specific marker for lymphatic endothelium, differentiates lymphatic from vascular endothelium. Guleria et al. in their article emphasized that LI and lymphangiogenesis, as opposed to blood vessel invasion, are better prognostic indicators in IDC breast.[2]

The manuscript by Sterlacci et al. recommends additional MUC5AC staining for thyroid transcription factor 1negative adenocarcinoma in the lung for the differentiation of a possible metastasis in the presence of pancreatic ductal adenocarcinoma.[3]

There has been a shift from the morphological and clinical classification to a more evolved molecular classification. This usually incorporates mutations in Janus kinase 2 (JAK2), MPL, and calreticulin (CALR) genes which carry not only diagnostic but also prognostic relevance. Rabade et al. have highlighted these features in an illustrative and descriptive manner.[4]

Urothelial carcinoma (UC) is one of the most frequent epithelial tumors worldwide. Turk et al. in their study investigated the protein expressions of caspase-8, p53, murine double minute 2 (mdm2), and p14ARF in nonmuscle UCs and correlated the findings with the clinical and pathological findings. They further observed that the staining pattern of caspase-8 may help in determining the stage in nonmuscle UC, whereas the expression of p53 and mdm2 relates to recurrence.[5]

Garg et al. in their article on core needle biopsies from four major organs, namely breast, prostate, soft tissue, and lymph nodes having surgical disorders emphasized the current practices of handling and reporting of core needle biopsies, mentioning their importance.[6] The article by Goyal et al. signifies the occurrence of various qualitative defects in patients with normal sperm counts, which were referred for baseline investigation.[7]

I am sure that more and more members would contribute their valuable research work to IJPM and also cite articles published in IJPM in all their submissions.

Jai Hind



 
   References Top

1.
Krothapalli M, Kini JR, Kini H, Sahu KK, Shenoy S, Krishna SG, et al. Evaluation of p53 protein expression in Barrett esophagus. Indian J Pathol Microbiol 2018;61:170-5.  Back to cited text no. 1
  [Full text]  
2.
Guleria P, Srinivas V, Basannar D, Dutta V. Comparison of lymphangiogenesis, lymphatic invasion, an axillary lymph node metastasis in breast carcinoma. Indian J Pathol Microbiol 2018;61:176-80.  Back to cited text no. 2
  [Full text]  
3.
Sterlacci W, Fieg IM, Veits L, Tzankov A. Diagnostic and prognostic impact of mucin 1-6 expression in non-small cell lung cancer. Indian J Pathol Microbiol 2018;61:187-91.  Back to cited text no. 3
  [Full text]  
4.
Rabade N, Subramanian PG, Kodgule R, Raval G, Joshi S, Chaudhary S, et al. Molecular genetics of BCR? ABL 1 negative myeloproliferative neoplasma in India. Indian J Pathol Microbiol 2018;61:209-13.  Back to cited text no. 4
  [Full text]  
5.
Turk NS, Eskicorapci S, Aybek Z, Tuncay L. The determination of stage in non muscle urothelial carcinoma: Staining pattern of Caspase8. Indian J Pathol Microbiol 2018;61:192-6.  Back to cited text no. 5
    
6.
Garg P, Pathak P, Goyal R, Arora VK, Singh N. Current practice in handling and reporting needle biopsies: A hospital based survey. Indian J Pathol Microbiol 2018;61:197-200.  Back to cited text no. 6
  [Full text]  
7.
Goyal R, Kotru M, Gogia A, Sharma S. Qualitative defects with normal sperm counts in a patient attending infertility clinic. Indian J Pathol Microbiol 2018;61:233-5.  Back to cited text no. 7
  [Full text]  

Top
Correspondence Address:
Ranjan Agrawal
MD; FICPath; MIAC, DHA Professor, Department of Pathology, Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.230586

Rights and Permissions




 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Email Alert *
    Add to My List *
* Registration required (free)  


    References

 Article Access Statistics
    Viewed897    
    Printed58    
    Emailed0    
    PDF Downloaded91    
    Comments [Add]    

Recommend this journal