Indian Journal of Pathology and Microbiology
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Year : 2019  |  Volume : 62  |  Issue : 1  |  Page : 95-98

Glomerulocystic disease, a rare cause of renal cysts in infants: A series of three cases


1 Department of Pathology, IPGME and R, Kolkata, West Bengal, India
2 Department of Neonatology, IPGME and R, Kolkata, West Bengal, India

Correspondence Address:
Uttara Chatterjee
Department of Pathology, IPGME and R, Kolkata, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/IJPM.IJPM_643_17

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Glomerulocystic kidney disease (GCKD) is an uncommon type of cystic renal disease affecting children. It has both sporadic and familial occurrence and is characterized by cortical microcysts associated with dilatation of Bowman's spaces. In some instances, GCKD is an early manifestation of autosomal dominant polycystic kidney disease. Here, we present three cases of GCKD, two in infants and one in a perinatal postmortem. The first one is a case of GCKD with unilateral involvement, diagnosed on surgical biopsy. GCKD is a morphological expression of several hereditary and nonhereditary disorders that differ vastly in their management and long-term outcome. Hence, accurate morphological diagnosis of this entity is important for prognostication and genetic counseling.


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