Indian Journal of Pathology and Microbiology


Year
: 1995  |  Volume : 38  |  Issue : 1  |  Page : 25--32

Nucleolar organizer regions in pituitary adenomas.


V V Radhakrishnan, N S Radhakrishnan, B K Misra, D Rout 
 Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum, India

Correspondence Address:
V V Radhakrishnan
Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Trivandrum, India

In this study, thirty-two non-functional and eighteen functional pituitary adenomas were analysed for the presence of argyrophilic nucleolar organizer regions (Ag-NORs) in paraffin sections, using an one-step silver-colloidal staining method. Differences in the mean Ag-NOR numbers of functional pituitary adenomas were statistically significant than those of non-functional pituitary adenomas. It is being emphasised that evaluation of Ag-NOR count is a more reliable index than the presence of mitotic figures in predicting the proliferative activity as well as possibility of recurrence in a patient with pituitary adenoma.


How to cite this article:
Radhakrishnan V, Radhakrishnan N, Misra B, Rout D. Nucleolar organizer regions in pituitary adenomas. Indian J Pathol Microbiol 1995;38:25-32


How to cite this URL:
Radhakrishnan V, Radhakrishnan N, Misra B, Rout D. Nucleolar organizer regions in pituitary adenomas. Indian J Pathol Microbiol [serial online] 1995 [cited 2020 Jul 13 ];38:25-32
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=1995;volume=38;issue=1;spage=25;epage=32;aulast=Radhakrishnan;type=0