Indian Journal of Pathology and Microbiology


Year
: 1995  |  Volume : 38  |  Issue : 3  |  Page : 257--60

Pregnancy induced hypertension and antithrombin-III.


M Srivastava, S Bali, J Pandey, V Nayar, V H Talib 
 Department of Obstetrics and Gynaecology, Safdarjang Hospital, New Delhi

Correspondence Address:
M Srivastava
Department of Obstetrics and Gynaecology, Safdarjang Hospital, New Delhi

This study was undertaken to determine the coagulation profile of women with pregnancy induced hypertension and to evaluate the changes in the level of AT-III in pre-eclampsia and eclampsia and its correlation with severity of disease in order to evaluate if it can be used as a marker for severity of PIH. 119 women with PIH in the third trimester of pregnancy constituted the study group. Age and parity matched 25 normal pregnant and 25 non-pregnant women were taken as control group. No significant difference between the coagulation profile of non-pregnant and normal pregnant women was seen. There is evidence of consumption coagulopathy in PIH patients and AT-III activity shows a gradual and almost linear reduction in various groups ranging from normal pregnant women to eclampsia. Reduction in AT-III activity has positive correlation with PIH and it can be a useful marker for severity of PIH.


How to cite this article:
Srivastava M, Bali S, Pandey J, Nayar V, Talib V. Pregnancy induced hypertension and antithrombin-III. Indian J Pathol Microbiol 1995;38:257-60


How to cite this URL:
Srivastava M, Bali S, Pandey J, Nayar V, Talib V. Pregnancy induced hypertension and antithrombin-III. Indian J Pathol Microbiol [serial online] 1995 [cited 2020 May 28 ];38:257-60
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=1995;volume=38;issue=3;spage=257;epage=60;aulast=Srivastava;type=0