Indian Journal of Pathology and Microbiology


Year
: 2001  |  Volume : 44  |  Issue : 2  |  Page : 117--21

Study of anticardiolipin antibodies in repeated abortions--an institutional experience.


J J Sheth, F J Sheth 
 Endocrine Unit, Dr. Shah's Pathology Laboratory, 1st Floor, Medicare Centre, B/H M.J. Library, Ellisbridge, Ahmedabad

Correspondence Address:
J J Sheth
Endocrine Unit, Dr. Shah«SQ»s Pathology Laboratory, 1st Floor, Medicare Centre, B/H M.J. Library, Ellisbridge, Ahmedabad

A cohort of 178 pregnant women with a history of first or second trimester abortions (2 or more) were the base of present study. In all, other causes of abortion were ruled out except for anti-phospholipid syndrome. Anti-Cardiolipin antibody (ACA) (IgG & IgM) was estimated in the sera samples of all women. Out of 178 women, any one or both immunoglobulins were above the cut off range (> 15.0 units) in 47 (26.4%) while both immunoglobulins were normal in 131 (73.59%) women. Both immunoglobulins were present in only 0.5% women. ACA-IgG alone was present in 11.79% while ACA-IgM alone was present in 14.04% women. We observe from present study that ACA is a major cause of recurrent fetal loss & many pregnancies can be saved if diagnosed & treated adequately.


How to cite this article:
Sheth J, Sheth F. Study of anticardiolipin antibodies in repeated abortions--an institutional experience. Indian J Pathol Microbiol 2001;44:117-21


How to cite this URL:
Sheth J, Sheth F. Study of anticardiolipin antibodies in repeated abortions--an institutional experience. Indian J Pathol Microbiol [serial online] 2001 [cited 2019 Aug 20 ];44:117-21
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2001;volume=44;issue=2;spage=117;epage=21;aulast=Sheth;type=0