Indian Journal of Pathology and Microbiology


Year
: 2002  |  Volume : 45  |  Issue : 3  |  Page : 247--54

Role of mitotic counts in the grading and prognosis of the breast cancer.


Chandrakant Patel, Kakinder Pal Sidhu, M J Shah, S M Patel 
 Department of Pathology, M P Ahah Cancer Hospital, Gujarat Cancer and Research Institute, Civil Campus, Ahmedabad

Correspondence Address:
Chandrakant Patel
Department of Pathology, M P Ahah Cancer Hospital, Gujarat Cancer and Research Institute, Civil Campus, Ahmedabad

100 Cases of invasive breast cancer were studied for Tumor type, Tumor site, Nodal Status, Mitotic counts, Nuclear pleomorphism, Tubule formation and Nottingham modification of Bloom Richardson Grading. The follow up of the 82 patients treated with surgery and adjuvant treatment was available. Mitotic activity index (MAI) counted with strict criteria of elston CW, emerged as one of the most significant prognostic parameter followed by overall grade in predicting Tumor free survival (TFS) for the patients. Mitotic count also correlated well with overall Grade and lymph node status in predicting the TFS. This parameter is very useful where advanced studies like flowcytometry and immunohistochemical studies of the cell proliferation marker are not available.


How to cite this article:
Patel C, Sidhu K, Shah M, Patel S. Role of mitotic counts in the grading and prognosis of the breast cancer. Indian J Pathol Microbiol 2002;45:247-54


How to cite this URL:
Patel C, Sidhu K, Shah M, Patel S. Role of mitotic counts in the grading and prognosis of the breast cancer. Indian J Pathol Microbiol [serial online] 2002 [cited 2020 Apr 7 ];45:247-54
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2002;volume=45;issue=3;spage=247;epage=54;aulast=Patel;type=0