Indian Journal of Pathology and Microbiology


Year
: 2006  |  Volume : 49  |  Issue : 3  |  Page : 452--4

Disseminated histoplasmosis mimicking laryngeal carcinoma from central India--a case report.


AM Phatak, I Bhattacharya, V Misra, Aruna Madan Prabhu, U Natraj 
 Department of Pathology, Jagjivan Ram Hospital, Mumbai

Correspondence Address:
A M Phatak
Department of Pathology, Jagjivan Ram Hospital, Mumbai

A 58 year old male, chronic smoker, with diabetes mellitus (Type II), residing in Madhya Pradesh presented with dysphagia, hoarseness, odynophagia and significant weight loss. Microlaryngoscopy showed reddish ulcerated area involving valleculae, and pharyngo-epiglottic fold. Histopathological examination showed foamy macrophages containing Histoplasma capsulatum. Patient initially responded to Azoles, relapsed three months after stopping the treatment and presented with oral lesions. Biopsy showed H. capsulatum, histologically as well as on culture. The mycelial phase converted to yeast phase on B.H.I.A. at 37 degrees C confirming the isolate as H. capsulatum. The patient responded well to amphotericin B.


How to cite this article:
Phatak A M, Bhattacharya I, Misra V, Prabhu AM, Natraj U. Disseminated histoplasmosis mimicking laryngeal carcinoma from central India--a case report. Indian J Pathol Microbiol 2006;49:452-4


How to cite this URL:
Phatak A M, Bhattacharya I, Misra V, Prabhu AM, Natraj U. Disseminated histoplasmosis mimicking laryngeal carcinoma from central India--a case report. Indian J Pathol Microbiol [serial online] 2006 [cited 2020 Jul 7 ];49:452-4
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2006;volume=49;issue=3;spage=452;epage=4;aulast=Phatak;type=0