Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2008  |  Volume : 51  |  Issue : 2  |  Page : 274--276

Embryonal rhabdomyosarcoma of the chest wall: A case report and review of the literature


Vijaya V Mysorekar1, K Harish2, Nalini Kilara3, Murali Subramanian3, AG Giridhar4 
1 Department of Pathology, M. S. Ramaiah Medical College and Hospital, Bangalore, India
2 Department of Surgical Oncology, M. S. Ramaiah Medical College and Hospital, Bangalore, India
3 Department of Medical Oncology, M. S. Ramaiah Medical College and Hospital, Bangalore, India
4 Department of Radiology, M. S. Ramaiah Medical College and Hospital, Bangalore, India

Correspondence Address:
Vijaya V Mysorekar
89, A.G.«SQ»s Office Colony, 5th Main, 6th Cross, New BEL Road, Bangalore - 560 054
India

Embryonal rhabdomyosarcoma is a soft-tissue sarcoma which has a predilection for the head and neck area, genitourinary tract and the extremities. We report a rare case of embryonal rhabdomyosarcoma of the chest wall in an 8-year-old girl, presenting as a destructive tumor in the rib and clinically and radiologically mimicking Ewing«SQ»s sarcoma. Histopathological examination showed a small round cell tumor. Immunohistochemically, the positivity for muscle markers desmin and myogenin in the tumor cells proved to be useful for making a definitive diagnosis of embryonal rhabdomyosarcoma. Cytogenetic analysis revealed a high level of aneuploidy in the tumor cells, with double-minutes and additional chromosomal structural aberrations. The patient is responding well to chemotherapy.


How to cite this article:
Mysorekar VV, Harish K, Kilara N, Subramanian M, Giridhar A G. Embryonal rhabdomyosarcoma of the chest wall: A case report and review of the literature.Indian J Pathol Microbiol 2008;51:274-276


How to cite this URL:
Mysorekar VV, Harish K, Kilara N, Subramanian M, Giridhar A G. Embryonal rhabdomyosarcoma of the chest wall: A case report and review of the literature. Indian J Pathol Microbiol [serial online] 2008 [cited 2020 Feb 25 ];51:274-276
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2008;volume=51;issue=2;spage=274;epage=276;aulast=Mysorekar;type=0