Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2009  |  Volume : 52  |  Issue : 3  |  Page : 417--420

Pure choriocarcinoma of ovary diagnosed by fine needle aspiration cytology


MR Naniwadekar, SR Desai, NS Kshirsagar, NN Angarkar, VD Dombale, SV Jagtap 
 Department of Pathology, Krishna Institute of Medical Sciences, Karad - 415 110, India

Correspondence Address:
M R Naniwadekar
Naniwadekar Hospital, Market Yard, Shaniwar Peth, Karad - 415 110, Dist - Satara, Maharashtra
India

Pure ovarian choriocarcinoma is extremely rare and can develop as a germ cell tumor or as a metastasis from uterine or tubal gestational choriocarcinoma or rarely from an ovarian pregnancy. The cytomorphologic findings have been reported previously in different sites. However, this is the first case of pure ovarian choriocarcinoma diagnosed on cytology to the best of our knowledge. The distinction between a gestational and nongestational choriocarcinoma is difficult. A 19-year-old female patient presented with an irregular per-vaginal bleeding and a mass in lower abdomen. Fine needle aspiration cytology smears of the mass were hypocellular and showed large, multinucleated giant cells and malignant mononucleated cells. Background was hemorrhagic. Serum β hCG level was 3,80,000 mIU/ml. A diagnosis of choriocarcinoma was offered which was later confirmed by histopathology. The diagnosis of choriocarcinoma on fine needle aspiration cytology is based on the presence of large, multinucleated giant cells and malignant mononucleated cells. A high index of suspicion should be maintained and estimation of serum β hCG plays a key role in supporting the diagnosis.


How to cite this article:
Naniwadekar M R, Desai S R, Kshirsagar N S, Angarkar N N, Dombale V D, Jagtap S V. Pure choriocarcinoma of ovary diagnosed by fine needle aspiration cytology.Indian J Pathol Microbiol 2009;52:417-420


How to cite this URL:
Naniwadekar M R, Desai S R, Kshirsagar N S, Angarkar N N, Dombale V D, Jagtap S V. Pure choriocarcinoma of ovary diagnosed by fine needle aspiration cytology. Indian J Pathol Microbiol [serial online] 2009 [cited 2019 Nov 22 ];52:417-420
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=3;spage=417;epage=420;aulast=Naniwadekar;type=0