Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2009  |  Volume : 52  |  Issue : 3  |  Page : 424--426

Congenital sideroblastic anemia: A report of two cases


Sanjeev Kumar Gupta, Seema Rao, Rakhee Kar, Seema Tyagi, Hara Prasad Pati 
 Department of Hematology, IRCH, All India Institute of Medical Sciences, Ansari Nagar, New Delhi -110 029, India

Correspondence Address:
Sanjeev Kumar Gupta
B-1/226, Yamuna Vihar, Delhi - 110 053
India

Sideroblastic anemia, comprising of acquired and congenital forms, is a heterogeneous group of disorders characterized by the presence of ring sideroblasts in the bone marrow. Congenital sideroblastic anemia is a rare condition which is mostly X-linked, caused by mutations of delta-aminolevulinic acid synthase 2. We describe two cases of congenital sideroblastic anemia, one of them indicating an autosomal recessive inheritance, with their clinico-hematological profile. It is important to recognize this entity early in life as a significant percentage of cases respond to pyridoxine thus avoiding any long-term complications.


How to cite this article:
Gupta SK, Rao S, Kar R, Tyagi S, Pati HP. Congenital sideroblastic anemia: A report of two cases.Indian J Pathol Microbiol 2009;52:424-426


How to cite this URL:
Gupta SK, Rao S, Kar R, Tyagi S, Pati HP. Congenital sideroblastic anemia: A report of two cases. Indian J Pathol Microbiol [serial online] 2009 [cited 2020 Apr 9 ];52:424-426
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=3;spage=424;epage=426;aulast=Gupta;type=0