Indian Journal of Pathology and Microbiology

CASE REPORT
Year
: 2010  |  Volume : 53  |  Issue : 1  |  Page : 112--114

Multiple intraductal papillomas of breast clinically masquerading as malignancy


Pallavi Singh, Vatsala Misra, Premala A Singh, Ravi Mehrotra 
 Department of Pathology, Moti Lal Nehru Medical College, Allahabad, India

Correspondence Address:
Vatsala Misra
Department of Pathology, M.L.N. Medical College, Allahabad - 211001
India

Background: Intraductal papilloma is characterized by proliferation of epithelial and myoepithelial cells overlying fibro-vascular stalks creating an arborescent structure within the lumen of duct. Some times multiple papillomas with florid proliferation of epithelium may be confused with malignancy. A case of multiple intraductal papillomas of breast with ulceration of overlying skin and large lump leading to clinical diagnosis of malignancy is documented here. Case Report: A 45-year-old female presented with ulcerated mass of six months duration in the left breast. On examination, a firm, immobile lump of 8× 10 cm in size involving nipple with excoriation of surrounding skin and serosanguinous discharge from nipple was present. There was no axillary lymphadenopathy. No family history of carcinoma breast was present. Fine needle aspiration smears showed benign cellular changes with apocrine metaplasia. Biopsy from an area adjacent to nipple showed intraductal papilloma. Simple mastectomy showed lobulated dirty white mass with well circumscribed nodules below the nipple and areola. On histology with immunohistochemistry a diagnosis of multiple intraductal papillomas was made. Patient is on regular follow-up and doing well. Conclusion: The case highlights the problem in differentiating marked papillomatosis from a malignant lesion of breast and importance of biopsy with immunohistochemistry in such cases for proper management.


How to cite this article:
Singh P, Misra V, Singh PA, Mehrotra R. Multiple intraductal papillomas of breast clinically masquerading as malignancy.Indian J Pathol Microbiol 2010;53:112-114


How to cite this URL:
Singh P, Misra V, Singh PA, Mehrotra R. Multiple intraductal papillomas of breast clinically masquerading as malignancy. Indian J Pathol Microbiol [serial online] 2010 [cited 2020 Feb 22 ];53:112-114
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2010;volume=53;issue=1;spage=112;epage=114;aulast=Singh;type=0