Indian Journal of Pathology and Microbiology

ORIGINAL ARTICLE
Year
: 2012  |  Volume : 55  |  Issue : 4  |  Page : 478--480

Molecular detection of TT virus and SEN virus infections in hemodialysed patients and blood donors in south of Iran


Rouhi Afkari1, Aliyar Pirouzi2, Mehdi Mohsenzadeh2, Mohammad Azadi2, Mohammad Jafari2 
1 Department of microbiology, Jahrom Branch, Young Researchers Club, Islamic Azad University, Jahrom, Iran
2 Department of microbiology, Gerash Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Correspondence Address:
Mohammad Jafari
Department of Shiraz University of Medical Sciences, Gerash Research Center, Gerash
Iran

Background: SEN virus (SEN-V) and TT virus (TTV) have been classified in the circoviridae family. Both are single-stranded, non-enveloped DNA viruses of about 3800 nucleotides. Patients on maintenance hemodialysis (HD) have a high risk of blood-borne viral infections. SEN-V and TTV has been reported from a number of HD units from various countries throughout the world. Materials and Methods: A total of 377 blood samples obtained from 150 healthy donors and 227 HD patients were collected at the HD center. SEN-V and TTV DNA was determined by polymerase chain reaction (PCR) in all samples. Results: TTV was detected in 109 (48.01%) of 227 hemodialysed patients and 14 (9.33%) of 150 voluntary blood donors (significant, P < 0.05). The PCR results for SEN-V-D/H DNA showed that 65 (28.63%) were positive for SEN-V-D and 33 (14.53%) were positive for SEN-V-H. 9.69% of 227 patients were positive for SEN-V-D/H co-infection. In the control group, SEN-V-D was detected in 14 (9.33%) and SEN-V-H was detected in 15 (10%) of the 150 (100%) blood donors. Conclusion: These findings show that the prevalence of SEN-V-D/H and TTV is higher than healthy blood donors. Also, these results indicate that the prevalence of SEN-V and TTV infections in our region is similar with that in other countries.


How to cite this article:
Afkari R, Pirouzi A, Mohsenzadeh M, Azadi M, Jafari M. Molecular detection of TT virus and SEN virus infections in hemodialysed patients and blood donors in south of Iran.Indian J Pathol Microbiol 2012;55:478-480


How to cite this URL:
Afkari R, Pirouzi A, Mohsenzadeh M, Azadi M, Jafari M. Molecular detection of TT virus and SEN virus infections in hemodialysed patients and blood donors in south of Iran. Indian J Pathol Microbiol [serial online] 2012 [cited 2020 Aug 14 ];55:478-480
Available from: http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=4;spage=478;epage=480;aulast=Afkari;type=0