FROM EDITORíS DESK
Year : 2019 | Volume
: 62 | Issue : 1 | Page : 1--2
From Editor's desk
MD; FICPath; MIAC, DHA Professor, Department of Pathology, Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh, India
MD; FICPath; MIAC, DHA Professor, Department of Pathology, Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh
|How to cite this article:|
Agrawal R. From Editor's desk.Indian J Pathol Microbiol 2019;62:1-2
|How to cite this URL:|
Agrawal R. From Editor's desk. Indian J Pathol Microbiol [serial online] 2019 [cited 2019 Apr 26 ];62:1-2
Available from: http://www.ijpmonline.org/text.asp?2019/62/1/1/251285
Wishing you all great wishes for the new year 2019. The January–March 2019 issue is now on your table. This issue contains a good number of interesting articles.
The article by Ekmekci et al. stated a relationship between tumor budding at the invasive tumor margin and clinicopathologic parameters and suggested that it may be used as a prognostic factor in squamous cell carcinoma larynx. Tumor budding as an adverse prognostic factor might be used to categorize the patients into risk groups, and the authors further emphasized that the pathology reports should include information about the presence or absence of tumor budding to predict the prognosis in these patients.
Karuna et al. in their article on the classification of salivary gland lesions as per the Milan system emphasized the need for categorizing each lesion so as to specify the risk of malignancy individually and further helping in the therapeutic management of these patients. It is also specified that the use of Milan system is more consistent since it provides uniformity in the reporting pattern. Well-differentiated tumors of uncertain malignant potential in thyroid include tumors that do not show define invasion but are considered to be borderline in nature. Immunohistochemistry markers such as CD56, P63, and CK19 are commonly used in differentiating between benign and malignant thyroid tumors. Computerized nuclear morphometry is an inexpensive and reproducible diagnostic tool in the histological evaluation of thyroid tumors.
Treatment of lung carcinomas requires the use of targeted therapy. Epidermal growth factor receptor and anaplastic lymphoma kinase mutational analysis has been implicated in well-differentiated adenocarcinomas of lung, especially the acinar types. The mucinous, mucinous cribriform, and papillary were found to be negative for ALK1 mutation, whereas EGFR mutations were seen in all groups except mucinous cribriform as reported by Gupta et al. A good correlation exists between the prognosis of colorectal carcinomas and the number of retrieved mesenteric lymph nodes showing metastatic deposits. Cakir et al. stated that at least 12 lymph nodes must be sampled for the complete evaluation of patients with colorectal carcinoma. For maximizing the yield of lymph nodes, use of ancillary methods such as fat clearance or special solutions by the surgical pathologist may be helpful.
Hepatitis C virus is characterized by a high degree of variability in the nucleotide sequencing between different genotypes. Halim et al. in their research concluded that few HCV4a-derived polypeptides hold good potential for use in the development of improved HCV immunodiagnostics. Introducing video-projected practical examination as a formative assessment tool in practical pathology is likely to enhance the learning and academic performance of students. Khan et al. in their research conducted on examiners and students showed that this newer system has several advantages over the conventional practical examination methodology.
Xanthomas of the gastrointestinal tract are rare lesions composed of collections of lipid-laden macrophages in the lamina propria. As it can histologically mimic malignant lesion, an accurate diagnosis of this entity is important.
I would again request all the life members of IAPM with number till L-2096 to update their address so that the hard copy of the journal reaches them. Reviewers are also requested to respond immediately regarding acceptance/declining of reviewing the article and to submit their reports early, thus reducing the turn-around time.
|1||Ekmekci S, Kucuk U, Kokkoz S, Cakir E, Gumussoy M. Tumor budding in laryngeal carcinoma. Indian J Pathol Microbiol 2019;62:7-10.|
|2||Karuna V, Gupta P, Rathi M, Grover K, Nigam JS, Verma N. Effectuation to cognize malignancy risk and accuracy of fine needle aspiration cytology in salivary gland using “Milan System for Reporting Salivary Gland Cytopathology”: A 2 years retrospective study in academic institution. Indian J Pathol Microbiol 2019;62:11-6.|
|3||Mohamed DA, Shamlola MM. Immunohistochemical and morphometrical evaluation of well-differentiated thyroid tumor of uncertain malignant potential. Indian J Pathol Microbiol 2019;62:17-23.|
|4||Gupta P, Gowrishankar S, Swain M. Epidermal growth factor receptor and anaplastic lymphoma kinase mutation in adenocarcinoma lung: Their incidence and correlation with histologic patterns. Indian J Pathol Microbiol 2019;62:24-30.|
|5||Cakir A, Turkmen IC, Akhan AU, Akkoc M, Korkmaz P. Second evaluation of the mesenteric tissue after ethanol fixation improved the total and metastatic number of lymph nodes in colorectal resections. Indian J Pathol Microbiol 2019;62:31-5.|
|6||Halim AS, Mohamed MR, Hamid FF, Karim AM. Expression and immune recognition of polypeptides derived from Hepatitis C virus structural proteins. Indian J Pathol Microbiol 2019;62:43-8.|
|7||Khan S, Hassan MJ, Husain M, Jetley S. Video projected video projected practical examination as an introducing formative assessment tool for undergraduate examination in pathology. Indian J Pathol Microbiol 2019;62:79-83.|
|8||Hasan F, Dighade S, Bind MK, Misra V. Clear cells in gastric biopsy, are they always neoplastic? Indian J Pathol Microbiol 2019;62:177-8.|