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  Indian J Med Microbiol
 

Figure 2: Hybrid schwannoma/perineurioma. (a) Cellular tumor exhibiting nesting and fascicular arrangement of spindle-shaped tumor cells with mild nuclear atypia. Inset showing focal degenerative atypia. (hematoxylin and eosin, ×200). (b) Immunohistochemistry showing epithelial membrane antigen positivity, highlighting spindle shaped perineurial cells. (Diaminobenzidine, ×200). (c) Inset showing cytoplasmic epithelial membrane antigen positivity in perineurial cells on higher magnification. Schwann cells exhibiting intense intranuclear S100-P positivity. (Diaminobenzidine, ×200). (d) Higher magnification showing intense S100P positive schwann cells. (Diaminobenzidine, ×400). (e) Low MIB1. (Diaminobenzidine, ×400)

Figure 2: Hybrid schwannoma/perineurioma. (a) Cellular tumor exhibiting nesting and fascicular arrangement of spindle-shaped tumor cells with mild nuclear atypia. Inset showing focal degenerative atypia. (hematoxylin and eosin, ×200). (b) Immunohistochemistry showing epithelial membrane antigen positivity, highlighting spindle shaped perineurial cells. (Diaminobenzidine, ×200). (c) Inset showing cytoplasmic epithelial membrane antigen positivity in perineurial cells on higher magnification. Schwann cells exhibiting intense intranuclear S100-P positivity. (Diaminobenzidine, ×200). (d) Higher magnification showing intense S100P positive schwann cells. (Diaminobenzidine, ×400). (e) Low MIB1. (Diaminobenzidine, ×400)