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  Indian J Med Microbiol
 

Figure 4: (a) Barrett esophagus with low-grade dysplasia showing hyperchromatic, enlarged, pleomorphic nuclei and mild loss of polarity (H and E, ×400). (b) Barrett esophagus with low-grade dysplasia showing p53 nuclear positivity (×400, p53 immunostain). (c) Mucosa showing distorted, irregular malignant glands with back-to-back arrangement (H and E, ×100). (d) Adenocarcinoma showing p53 nuclear positivity (×400, p53 immunostain)

Figure 4: (a) Barrett esophagus with low-grade dysplasia showing hyperchromatic, enlarged, pleomorphic nuclei and mild loss of polarity (H and E, ×400). (b) Barrett esophagus with low-grade dysplasia showing p53 nuclear positivity (×400, p53 immunostain). (c) Mucosa showing distorted, irregular malignant glands with back-to-back arrangement (H and E, ×100). (d) Adenocarcinoma showing p53 nuclear positivity (×400, p53 immunostain)