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  Indian J Med Microbiol
 

Figure 9: Case of plasma cell tumor, referred as a malignant round cell tumor (a-b). (a) Plasma cells, focally arranged around blood vessel (H and E, ×400). (b) Diffuse CD138/syndecan-1 positivity (Diaminobenzidine, ×400). (c) Case of Langerhans's cell histiocytosis (LCH), in form of a lytic lesion in lower humerus, with periosteal reaction (double contour). (d) Microscopy: Eosinophils, multinucleate giant cells and polygonal cells with intranuclear grooves (H and E, ×400). (e) S100 protein positivity (Diaminobenzidine, ×200). (f) CD1a positivity (Diaminobenzidine, ×200)

Figure 9: Case of plasma cell tumor, referred as a malignant round cell tumor (a-b). (a) Plasma cells, focally arranged around blood vessel (H and E, ×400). (b) Diffuse CD138/syndecan-1 positivity (Diaminobenzidine, ×400). (c) Case of Langerhans's cell histiocytosis (LCH), in form of a lytic lesion in lower humerus, with periosteal reaction (double contour). (d) Microscopy: Eosinophils, multinucleate giant cells and polygonal cells with intranuclear grooves (H and E, ×400). (e) S100 protein positivity (Diaminobenzidine, ×200). (f) CD1a positivity (Diaminobenzidine, ×200)