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  Indian J Med Microbiol
 

Figure 2: (a and b) Areas displaying pleomorphic xanthoastrocytoma (PXA) morphology: Spindle cells, scattered pleomorphic giant cells and microcystic spaces [H and E, 200×]. (c) Reticulin stain in this area showed fibrils surrounding both individual cells and small nests [reticulin, 200×]. (d) Gangliogliomatous (GG) areas showed dysplastic ganglionic cells with irregular nuclei, inset showing higher power [H and E, 400×]. (e, g and h) Nests of GG admixed with short fascicles of PXA [H and E, 200×]. (f) Reticulin fibrils outlining cells in GG areas [reticulin, 200×]. (i) Glial fibrillary acid protein (GFAP) immunopositivity confined to the spindle cells in the PXA area [GFAP, 200×]

Figure 2: (a and b) Areas displaying pleomorphic xanthoastrocytoma (PXA) morphology: Spindle cells, scattered pleomorphic giant cells and microcystic spaces [H and E, 200×]. (c) Reticulin stain in this area showed fibrils surrounding both individual cells and small nests [reticulin, 200×]. (d) Gangliogliomatous (GG) areas showed dysplastic ganglionic cells with irregular nuclei, inset showing higher power [H and E, 400×]. (e, g and h) Nests of GG admixed with short fascicles of PXA [H and E, 200×]. (f) Reticulin fibrils outlining cells in GG areas [reticulin, 200×]. (i) Glial fibrillary acid protein (GFAP) immunopositivity confined to the spindle cells in the PXA area [GFAP, 200×]