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  Indian J Med Microbiol
 

Figure 2: Case 2: (a) MRI examination of the primary lesion shows a tumor in the left frontal lobe that had T2WI iso- to hyperintensity. (b) The tumors exhibit high cell densities, composed of primitive, poorly differentiated, small cells with sparse cytoplasm, and brisk mitotic activity (×400). (c) Tumor cells show dissemination to the subarachnoid spaces (×200). (d) Tumor cells are positive for GFAP. (e) Tumor cells are positive for p53. (f) Tumor cells are positive for H3.3 G34R. (g) Tumor cells are negative for Olig2. (h) Tumor cells are negative for ATRX. (i) Tumor cells are negative for H3 K27M

Figure 2: Case 2: (a) MRI examination of the primary lesion shows a tumor in the left frontal lobe that had T2WI iso- to hyperintensity. (b) The tumors exhibit high cell densities, composed of primitive, poorly differentiated, small cells with sparse cytoplasm, and brisk mitotic activity (×400). (c) Tumor cells show dissemination to the subarachnoid spaces (×200). (d) Tumor cells are positive for GFAP. (e) Tumor cells are positive for p53. (f) Tumor cells are positive for H3.3 G34R. (g) Tumor cells are negative for Olig2. (h) Tumor cells are negative for ATRX. (i) Tumor cells are negative for H3 K27M