Close
  Indian J Med Microbiol
 

Figure 1: (a) Cutaneous leiomyoma in HLRCC resembles a regular piloleiomyoma forming a dermal nodule (×20); (b) Atypical intradermal smooth muscle neoplasm demonstrating mitotic activity (note inset, 200x) without significant nuclear pleomorphism in an HLRCC case (×100); (c) Loss of fumarate hydratase expression by immunohistochemistry in a cutaneous leiomyoma (immunoperoxidase, ×200); (d) Uterine leiomyosarcoma in HLRCC with a glistening myxoid gross appearance in a hysterectomy specimen; (e) Uterine leiomyosarcoma with necrosis and significant nuclear pleomorphism in a patient with HLRCC (×100); (f) High-power view of uterine leiomyosarcoma depicted in Figure 1e with elevated mitotic activity (arrows) but lacking the well-described features of prominent macronucleoli and perinuclear haloes; (hematoxylin and eosin staining, except C)

Figure 1: (a) Cutaneous leiomyoma in HLRCC resembles a regular piloleiomyoma forming a dermal nodule (×20); (b) Atypical intradermal smooth muscle neoplasm demonstrating mitotic activity (note inset, 200x) without significant nuclear pleomorphism in an HLRCC case (×100); (c) Loss of fumarate hydratase expression by immunohistochemistry in a cutaneous leiomyoma (immunoperoxidase, ×200); (d) Uterine leiomyosarcoma in HLRCC with a glistening myxoid gross appearance in a hysterectomy specimen; (e) Uterine leiomyosarcoma with necrosis and significant nuclear pleomorphism in a patient with HLRCC (×100); (f) High-power view of uterine leiomyosarcoma depicted in Figure 1e with elevated mitotic activity (arrows) but lacking the well-described features of prominent macronucleoli and perinuclear haloes; (hematoxylin and eosin staining, except C)