Indian Journal of Pathology and Microbiology
Home About us Instructions Submission Subscribe Advertise Contact e-Alerts Ahead Of Print Login 
Users Online: 1291
Print this page  Email this page Bookmark this page Small font sizeDefault font sizeIncrease font size
Year : 1995  |  Volume : 38  |  Issue : 4  |  Page : 369-74

Disk diffusion susceptibility testing of dermatophytes with imidazoles.

Institute of Microbiology, Madurai Medical College

Correspondence Address:
P V Venugopal
Institute of Microbiology, Madurai Medical College

Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 9726146

Rights and PermissionsRights and Permissions

In vitro susceptibility testing of 43 isolates of dermatophytes was carried out against imidazoles-ketoconazole, miconazole and econazole and griseofulvin by agar dilution and disk diffusion methods. Econazole was the most effective drug inhibiting all the isolates at a concentration of 0.1 microgram ml-1. The MIC 50s and MIC 90s for ketoconazole and miconazole were 1 and 2.5 mg ml-1 whereas the values for griseofulvin were 1 and 5 micrograms ml-1. Good correlation was seen between the MIC and sizes of zones of inhibition around the disks. Regression analysis was used to measure the degree of correlation between the MIC values and matched averaged zones of inhibition and the correlation coefficients for econazole, ketoconazole, miconazole and griseofulvin were -0.5554, -0.5886, -0.8558 and -0.8268 (p < 0.001) respectively.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded121    
    Comments [Add]    
    Cited by others 4    

Recommend this journal