Indian Journal of Pathology and Microbiology
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Year : 1997  |  Volume : 40  |  Issue : 4  |  Page : 559-61

Bisalbuminemia : an interesting electrophoretic abnormality--a report of two cases.

Department of Microbiology, Government Medical College, Nagpur

Correspondence Address:
Y S Thakar
Department of Microbiology, Government Medical College, Nagpur

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Source of Support: None, Conflict of Interest: None

PMID: 9444873

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We hereby report two cases of Bisalbuminemia for its extreme rarity in Indian literature. In an attempt to look for 'M' component, polyacrylamide gel disc electrophoresis of serum displayed observation. The saline eluates of the slower (variant in our cases) and the faster component showed a reaction of complete identify in the agar gel double diffusion test when tested against monospecific antialbumin antibody. The immunoelectrophoretic analysis also confirmed the antigenic similarity between the two fractions. A wider use of disc electrophoresis perhaps would disclose additional cases of Bisalbuminemia in normals and in disease states.

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