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Indian Journal of Pathology and Microbiology
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Year : 1999  |  Volume : 42  |  Issue : 3  |  Page : 327-32

Connective tissue stromal changes in tumours and tumour-like lesions of the breast.


Department of Pathology, Kasturba Medical College, Mangalore

Correspondence Address:
M R Pai
Department of Pathology, Kasturba Medical College, Mangalore

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Source of Support: None, Conflict of Interest: None


PMID: 10862293

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Between June 1994 and December 1995, one hundred and fifteen tumours and tumour-like lesions of the breast were studied in the Department of Pathology, Kasturba Medical College, Mangalore. Neoplasms constituted 80.9% and tumour like lesions accounted for 19.13%. Among the tumours, 51.6% were benign and 48.4% were malignant. Tumour-like lesions included the entire spectrum of fibrocystic disease. Tumours were common between 2nd and 8th decades while tumour-like lesions were uncommon above 6th decade. Whereas benign tumours exhibited ground substance, collagen and reticulin fibres in varying amounts, tumour-like lesions and carcinoma showed more of collagen fibres and less of ground substance. Elastosis and lymphoplasmacytic infiltrate were prominent features in carcinomas rather than in benign lesions.


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