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Indian Journal of Pathology and Microbiology
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Year : 2001  |  Volume : 44  |  Issue : 3  |  Page : 329-32

Desmoplastic astrocytoma of infancy--a case report.


B.Y.L. Nair Ch. Hospital & T.N.M. College, Mumbai Central, Mumbai

Correspondence Address:
B Kandalkar
B.Y.L. Nair Ch. Hospital & T.N.M. College, Mumbai Central, Mumbai

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Source of Support: None, Conflict of Interest: None


PMID: 12024924

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Desmoplastic cerebral astrocytoma of infancy (DCAI) is a rare tumor which shows spindle cells embedded in an extremely desmoplastic stroma. We describe a case of DCAI seen in the frontoparietal region of brain in a three-month-old infant. Microscopically classic histology of DCAI was seen. On immunohistochemistty the tumor showed strong Vimentin, S-100 and Glial Fibrillary Acidic Protein (GFAP) positivity. The brain adjacent to the tumor-showed multi-cystic transformation and the tumor formed a solid area in the wall of this cystic structure. This adjacent brain showed mild disarray of architecture and gliosis. Three months after surgery this infant was alive and well.


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