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Indian Journal of Pathology and Microbiology
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CASE REPORT
Year : 2009  |  Volume : 52  |  Issue : 1  |  Page : 74-76

Malignant peripheral nerve sheath tumor with divergent differentiation


1 Department of Pathology, Sri Devaraj Urs Medical College, Sri Devaraj Urs University, Tamaka, Kolar 563 101, India
2 Department of Surgery, Sri Devaraj Urs Medical College, Sri Devaraj Urs University, Tamaka, Kolar 563 101, India

Correspondence Address:
T N Suresh
Department of Pathology, Sri Devaraj Urs Medical College, Sri Devaraj Urs University, Tamaka, Kolar 563 101
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.44971

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A malignant peripheral nerve sheath tumor (MPNST) is an uncommon spindle cell sarcoma accounting for approximately 5% of all soft tissue sarcomas. A 55-year-old female with a right suprarenal tumor showed MPNST with additional foci of epithelioid, rhabdomyoblastic, osteogenic and lipogenic differentiation. Although the capacity of MPNST to undergo epithelioid, rhabdomyoblastic, osteogenic and very rarely lipogenic differentiation is reported in literature, the occurrence of all these differentiation in one case has not been described in literature before. To the best of our knowledge, this is only the second MPNST case with lipomatous differentiation


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