Indian Journal of Pathology and Microbiology
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Year : 2009  |  Volume : 52  |  Issue : 2  |  Page : 159-163

Quick score of hormone receptor status of breast carcinoma: Correlation with the other clinicopathological prognostic parameters

Department of Pathology, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka

Correspondence Address:
Lakmini K.B Mudduwa
Department of Pathology, Faculty of Medicine, University of Ruhuna, Galle
Sri Lanka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.48906

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Background: Immunohistochemical assessment of the hormone receptor status of breast carcinoma is a routine investigation. However, there is no worldwide consensus on the scoring system. The Quick Score is claimed to be a reliable scoring system, which assesses both the proportion of stained cells and the intensity of staining. Aims: To assess the value of Quick Score in terms of accepted clinicopathological parameters and to document the prevalence of hormone receptor-positive breast carcinomas in the study sample. Materials and Methods: Clinicopathological parameters of 151 breast cancers were compared with the Quick Scores for estrogen receptor (ER) and progesterone receptor (PR) status. Results and Conclusions: The Quick Score for ER was 0 in 54.3% (82/151) and for PR was 0 in 51.7% (75/145), indicating no hormone receptor expression in the majority. The Nottingham grade and the mitotic count had a significant inverse relationship with the Quick Score for hormone receptor status. The Nottingham Prognostic Index (NPI) also had an inverse relationship with the hormone receptor status.

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