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Indian Journal of Pathology and Microbiology
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CASE REPORT
Year : 2010  |  Volume : 53  |  Issue : 3  |  Page : 541-543

Papillary renal cell carcinoma with lipocyte-like cells: A rare morphological variant or an indication of aggressiveness?


1 Department of Pathology, Izmir Ataturk Training and Research Hospital, Izmir, Turkey
2 Department of Urology, Izmir Ataturk Training and Research Hospital, Izmir, Turkey

Correspondence Address:
Aysegul Sari
Ataturk Caddesi, Firat Apt. No:184, Kat:3 Daire:6 Alsancak-Izmir
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0377-4929.68291

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Papillary renal cell carcinoma (PRCC) is the second most common carcinoma of the kidney, which is classified into two types. Type 1 displays single layer of cells with scanty pale cytoplasm and type 2 has pseudostratified high-grade nuclei with eosinophilic cytoplasm. Recently, apart from these two types, oncocytic PRCC and clear-cell PRCC have been described. To the best of our knowledge, lipocyte-like cells have not yet been reported to accompany any subtypes of renal cell carcinoma. Herein, we report a case of PRCC with lipocyte-like cells and sarcomatoid features. Lipocyte-like cells might represent a special type of PRCC or this feature may be an indication of poor prognosis regarding its association with sarcomatoid change.


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