Indian Journal of Pathology and Microbiology
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Year : 2010  |  Volume : 53  |  Issue : 4  |  Page : 785-786

Primary osteogenic sarcoma of the breast

Department of Pathology, Christian Medical College & Hospital, Ludhiana, India

Correspondence Address:
Sunitha Jacob
Professor, Department of Pathology, Christian Medical College & Hospital, Ludhiana-141 008, Punjab
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.72090

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Primary osteogenic sarcomas of the breast are extremely rare with less than 100 cases reported in literature. They generally present in middle aged and older women and are highly aggressive. These tumors need to be differentiated from osteoid/bone- producing metaplastic carcinomas as the two differ in their biologic behavior and treatment protocols. A 60-year-old lady presented with a short history of a rapidly enlarging breast lump. Histopathogical examination revealed a richly cellular, pleomorphic tumor with abundant osteoid. The tumor cells were immunoreactive for vimentin and negative for cytokeratin and estrogen and progesterone receptors.

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