Indian Journal of Pathology and Microbiology
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Year : 2010  |  Volume : 53  |  Issue : 4  |  Page : 802-804

Benign metastasizing leiomyoma

Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan

Correspondence Address:
Saira Fatima
Department of Pathology & Microbiology, Aga Khan University Hospital, Stadium Road, Karachi - 74800
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0377-4929.72099

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Benign metastasizing leiomyoma (BML) is a rare condition, affecting predominantly reproductive-age females with uterine leiomyomata and is most often associated with multiple benign-appearing smooth muscle tumors in lungs. We report herein a case of a 38-year-old woman who presented with multiple uterine fibroids for which hysterectomy was carried out on her. Postoperatively, she developed left-sided pleural effusion. Computed chest tomography (CT) scan revealed multiple nodules in both lungs and pleurae. Histopathology of one of the pleura-based nodules revealed a neoplasm composed of interlacing fascicles of spindle cells with uniform nuclei. The tumor cells were positive for alpha-smooth muscle actin and negative for CD34 immunohistochemical stain.

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